Glucose enters our body through our digestion process. The daily food that we eat contain carbohydrates that are broken down by pancreatic enzymes into glucose. Glucose is the simple sugar that our body and cell use for energy. This energy in the form of ATP (adenosine tri phospate) is created through the pathway of glycolysis, the critic acid cycle, and electron transport.
In glycolysis, there are 10 reactionary steps that occurs to transform glucose into two pyruvates and two ATPs. In reaction 1, Glucose gets phosphorylated by hexokinase to form Glucose-6-phosphate. In reaction 2, Glucose-6-phospate gets isomerize by phosphogluco-isomerase into fructose-6-phosphate. In reaction 3, phosphorylation of fructose-6-phosphate by phospho-fructokinase forms fructose-1,6-biphosphate. In reaction 4, fructos-1,6-bisphosphate gets cleave by aldolase into two triose phosphates. in reaction 5, the isomerization of triose phosphates forms glyceraldehyde 3-phosphate. In reaction 6, glyceraldehyde 3-phosphate gets oxidized. In reaction 7, substrate-level phosphorylation forms 3-phosphoglycerate and ATP. In reaction 8, 3-phosphoglycerate gets isomerized to form 2-phosphoglycerate. in reaction 9, 2-phosphoglycerate gets dehydrated to form phosphoenolpyruvate. Lastly in reaction 10, the coupling reaction of hydrolysis and phosphorylation on phosphoenolpyruvate forms pyruvate and ATP. The end product of glycolysis is two pyruvate and two ATP.
The two pyruvates can be metabolized further into three separate pathways depending on the presence of oxygen and the organism. For plants and animal and under aerobic conditions, the pyruvates enters the critic acid cycle and electron transport reaction to produce 32 to 34 ATPs for our cell's usage.
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